What is weight loss medication? | how it works? | diet pills side effect | dangers of slimming pills



What is weight loss medication? | how it works? | diet pills side effect | dangers of slimming pills

#Nutritiontalk
Are you looking for a little extra help to lose weight? If so, you've got plenty of options from which to choose. Diet pills and supplements are widely available in vitamin stores, online and in health clubs. And several prescription diet medications have been approved by the Food and Drug Administration.

But are any of them really effective? And more importantly, are they safe? this video will help you find answer

here are some medication that are commonly used for weight loss purpose

anti - obesity medication

Phentermine
Orlistat
Phentermine/
topiramate
Lorcaserin
Bupropion/
naltrexone
Liraglutide


Phentermine
Approved by FDA in 1959
Mechanism: releases norepinephrine
Short term use (3 to 6 months)
Not approved for long term use
Cheap
Phentermine
Orlistat
Phentermine/
topiramate
Lorcaserin
Bupropion/
naltrexone
Liraglutide

Orlistat
Approved by FDA in 1999
Mechanism: inhibits lipase (gastric and pancreatic)
Therefore, decrease in fat breakdown and absorption
Side effects: GI disturbance (cramps, fecal incontinence, diarrhea (specifically steatorrhea)), fat soluble vitamin deficiency (vitamins DEAK) give multivitamins
Good for CAD patients or those at risk for CVD

✓Available over-the-counter

Phentermine
Orlistat
Phentermine/
topiramate
Lorcaserin
Bupropion/
naltrexone
Liraglutide

Phentermine/topiramate
Approved by FDA in 2010
Phentermine mechanism: releases norepinephrine
Topiramate mechanism: blocks Na channels, modulates GABA receptor to increase action
Used for migraine prophylaxis and seizures (simple, complex, tonic-clonic)
Side effects: mental sedation, kidney stones


Lorcaserin
Approved by FDA in 2012
Mechanism: agonists serotonin (5-HT2C) receptor
Side effects: dizziness, dry mouth, GI disturbance (nausea, vomiting, diarrhea), fatigue, headaches


Bupropion/naltrexone
Approved by FDA in 2014
Bupropion mechanism: increase norepinephrine and dopamine levels
Naltrexone mechanism: opioid antagonist
Side effects: anxiety, headaches
Good for patients also struggling with smoking cessation (bupropion approved for smoking cessation)


Liraglutide
Approved by FDA in 2015
Mechanism: agonizes the GLP-1 receptor (GLP-1 analog)
Subcutaneous injection
Side effects: pancreatitis, nausea, vomiting
Phentermine
Orlistat
Phentermine/
topiramate
Lorcaserin
Bupropion/
naltrexone
Liraglutide

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